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Interpretable systems biomarkers predict response to immune-checkpoint inhibitors

Cancer cells can leverage several cell-intrinsic and -extrinsic mechanisms to escape immune system recognition. The inherent complexity of the tumor microenvironment, with its multicellular and dynamic nature, poses great challenges for the extraction of biomarkers of immune response and immunothera...

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Detalles Bibliográficos
Autores principales:	Lapuente-Santana, Óscar, van Genderen, Maisa, Hilbers, Peter A.J., Finotello, Francesca, Eduati, Federica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369166/ https://www.ncbi.nlm.nih.gov/pubmed/34430923 http://dx.doi.org/10.1016/j.patter.2021.100293

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