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Downregulation of CD45 Signaling in COVID-19 Patients Is Reversed by C24D, a Novel CD45 Targeting Peptide

CD45, the predominant transmembrane tyrosine phosphatase in leukocytes, is required for the efficient induction of T cell receptor signaling and activation. We recently reported that the CD45-intracellular signals in peripheral blood mononuclear cells (PBMCs) of triple negative breast cancer (TNBC)...

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Detalles Bibliográficos
Autores principales: Alon, Danny, Paitan, Yossi, Robinson, Eyal, Ganor, Nirit, Lipovetsky, Julia, Yerushalmi, Rinat, Cohen, Cyrille J., Raiter, Annat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369232/
https://www.ncbi.nlm.nih.gov/pubmed/34414199
http://dx.doi.org/10.3389/fmed.2021.675963