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Exploring the Application of Bifunctional Metal Chelators in Treating Triple-Negative Breast Cancer
Purpose: In this study, we independently synthesised and labelled a novel bidentate bifunctional chelating agent, (177)Lu-3,4-HOPO-Cetuximab, that achieved tight binding between targeting and radioactivity, and evaluated its targeted killing ability of cells in vitro and in vivo. Method: 3,4-HOPO wa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369237/ https://www.ncbi.nlm.nih.gov/pubmed/34414172 http://dx.doi.org/10.3389/fbioe.2021.697862 |