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Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma

Inhaled allergens promote inflammatory response, tissue damage, and airway hyperresponsiveness in the lungs, leading to allergic asthma. NLRP3, as an immune sensor of infections and cellular stress, is associated with the development and exacerbation of asthma. However, the mechanism by which NLRP3...

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Detalles Bibliográficos
Autores principales: Ma, Ming, Li, Guoyang, Qi, Minghui, Jiang, Wei, Zhou, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369415/
https://www.ncbi.nlm.nih.gov/pubmed/34413860
http://dx.doi.org/10.3389/fimmu.2021.718779