High-Throughput Drug Screening System Based on Human Induced Pluripotent Stem Cell-Derived Atrial Myocytes ∼ A Novel Platform to Detect Cardiac Toxicity for Atrial Arrhythmias

Evaluation of proarrhythmic properties is critical for drug discovery. In particular, QT prolongation in electrocardiograms has been utilized as a surrogate marker in many evaluation systems to assess the risk of torsade de pointes and lethal ventricular arrhythmia. Recently, new evaluation systems...

Descripción completa

Detalles Bibliográficos
Autores principales: Honda, Yayoi, Li, Jun, Hino, Aya, Tsujimoto, Shinji, Lee, Jong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369502/
https://www.ncbi.nlm.nih.gov/pubmed/34413773
http://dx.doi.org/10.3389/fphar.2021.680618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369502/
https://www.ncbi.nlm.nih.gov/pubmed/34413773
http://dx.doi.org/10.3389/fphar.2021.680618

Ejemplares similares