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Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams–Beuren Syndrome Mice by Regulation of MAPK Pathway and Microglia Overexpression

Williams–Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by a distinctive cognitive phenotype for which there are currently no effective treatments. We investigated the progression of behavioral deficits present in WBS complete deletion (CD) mice, after chronic treatment wi...

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Detalles Bibliográficos
Autores principales: Ortiz-Romero, Paula, González-Simón, Alejandro, Egea, Gustavo, Pérez-Jurado, Luis A., Campuzano, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369570/
https://www.ncbi.nlm.nih.gov/pubmed/34413771
http://dx.doi.org/10.3389/fphar.2021.670785