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Metformin exerts anti-AR-negative prostate cancer activity via AMPK/autophagy signaling pathway

BACKGROUND: Encouraged by the goal of developing an effective treatment strategy for prostate cancer, this study explored the mechanism involved in metformin-mediated inhibition of AR-negative prostate cancer. METHODS: Cell behaviors of DU145 and PC3 cells were determined by CCK8 test, colony format...

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Detalles Bibliográficos
Autores principales: Chen, Chunyang, Wang, He, Geng, Xinyu, Zhang, Dongze, Zhu, Zhengyu, Zhang, Guangbo, Hou, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369631/
https://www.ncbi.nlm.nih.gov/pubmed/34399755
http://dx.doi.org/10.1186/s12935-021-02043-2