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Metformin exerts anti-AR-negative prostate cancer activity via AMPK/autophagy signaling pathway
BACKGROUND: Encouraged by the goal of developing an effective treatment strategy for prostate cancer, this study explored the mechanism involved in metformin-mediated inhibition of AR-negative prostate cancer. METHODS: Cell behaviors of DU145 and PC3 cells were determined by CCK8 test, colony format...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369631/ https://www.ncbi.nlm.nih.gov/pubmed/34399755 http://dx.doi.org/10.1186/s12935-021-02043-2 |