Pharmacological activation of rev-erbα suppresses LPS-induced macrophage M1 polarization and prevents pregnancy loss

BACKGROUND: Circadian rhythm is an important player for reproduction. Rev-erbα, a significant clock gene, is involved in regulating cell differentiation, inflammation and metabolism. Macrophage polarization plays crucial roles in immune tolerance at the maternal-fetus interface, which also modulates...

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Detalles Bibliográficos
Autores principales: Cui, Liyuan, Xu, Feng, Wang, Songcun, Li, Xinyi, Lin, Haiyan, Ding, Yan, Du, Meirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369701/
https://www.ncbi.nlm.nih.gov/pubmed/34399700
http://dx.doi.org/10.1186/s12865-021-00438-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369701/
https://www.ncbi.nlm.nih.gov/pubmed/34399700
http://dx.doi.org/10.1186/s12865-021-00438-4

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