Cargando…

Pharmacological activation of rev-erbα suppresses LPS-induced macrophage M1 polarization and prevents pregnancy loss

BACKGROUND: Circadian rhythm is an important player for reproduction. Rev-erbα, a significant clock gene, is involved in regulating cell differentiation, inflammation and metabolism. Macrophage polarization plays crucial roles in immune tolerance at the maternal-fetus interface, which also modulates...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Liyuan, Xu, Feng, Wang, Songcun, Li, Xinyi, Lin, Haiyan, Ding, Yan, Du, Meirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369701/ https://www.ncbi.nlm.nih.gov/pubmed/34399700 http://dx.doi.org/10.1186/s12865-021-00438-4

Ejemplares similares

Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis
por: Cui, Liyuan, et al.
Publicado: (2022)

Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
por: Cho, Han, et al.
Publicado: (2012)

The Nuclear Receptor and Clock Repressor Rev-erbα Suppresses Myogenesis
por: Chatterjee, Somik, et al.
Publicado: (2019)

REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output
por: Ikeda, Ryosuke, et al.
Publicado: (2019)

Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
por: Amador, Ariadna, et al.
Publicado: (2016)

Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
por: Amador, Ariadna, et al.
Publicado: (2018)

Direct and Indirect Suppression of Interleukin-6 Gene Expression in Murine Macrophages by Nuclear Orphan Receptor REV-ERBα
por: Sato, Shogo, et al.
Publicado: (2014)

Author Correction: The Nuclear Receptor and Clock Repressor Rev-erbα Suppresses Myogenesis
por: Chatterjee, Somik, et al.
Publicado: (2022)

Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway
por: Zou, Runmei, et al.
Publicado: (2023)

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene induced senescence
por: Sulli, Gabriele, et al.
Publicado: (2018)

Novel Function of Rev-erbα in Promoting Brown Adipogenesis
por: Nam, Deokhwa, et al.
Publicado: (2015)

Rev-erbα in the brain is essential for circadian food entrainment
por: Delezie, Julien, et al.
Publicado: (2016)

Targeting REV-ERBα for therapeutic purposes: promises and challenges
por: Wang, Shuai, et al.
Publicado: (2020)

Downregulation of REV-ERBα is associated with the progression of lung adenocarcinoma
por: Zhang, Hao, et al.
Publicado: (2022)

Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev‐Erbα in osteoblasts
por: Tian, Yihao, et al.
Publicado: (2022)

Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model
por: Yue, Jiong, et al.
Publicado: (2020)

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication
por: Borrmann, Helene, et al.
Publicado: (2020)

REV-ERB activation as a novel pharmacological approach for treating inflammatory pain
por: Makhija, Sangeet, et al.
Publicado: (2023)

Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts
por: Gillis, Sean P., et al.
Publicado: (2021)

The Nuclear Receptor Rev-erbα Controls Circadian Thermogenic Plasticity
por: Gerhart-Hines, Zachary, et al.
Publicado: (2013)

REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor
por: Okabe, Takashi, et al.
Publicado: (2016)

REV-ERBα Regulates T(H)17 Cell Development and Autoimmunity
por: Amir, Mohammed, et al.
Publicado: (2018)

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
por: Lam, Michael T.Y., et al.
Publicado: (2013)

Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
por: Amador, Ariadna, et al.
Publicado: (2016)

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis
por: Le Martelot, Gwendal, et al.
Publicado: (2009)

Translational Regulation of Clock Genes BMAL1 and REV-ERBα by Polyamines
por: Sakamoto, Akihiko, et al.
Publicado: (2021)

Direct Regulation of CLOCK Expression by REV-ERB
por: Crumbley, Christine, et al.
Publicado: (2011)

Rev-erbs and Glia—Implications for Neurodegenerative Diseases
por: Griffin, Percy, et al.
Publicado: (2019)

REV-ERB is essential in cardiac fibroblasts homeostasis
por: Luo, Xiaokang, et al.
Publicado: (2022)

The Role of REV-ERB Receptors in Cancer Pathogenesis
por: Gomatou, Georgia, et al.
Publicado: (2023)

Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
por: Amador, Ariadna, et al.
Publicado: (2016)

Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle
por: Welch, Ryan D., et al.
Publicado: (2017)

Decidual Stromal Cell Ferroptosis Associated with Abnormal Iron Metabolism Is Implicated in the Pathogenesis of Recurrent Pregnancy Loss
por: Sun, Fengrun, et al.
Publicado: (2023)

The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation
por: Yamashita, Kohei, et al.
Publicado: (2014)

Mildly Increased Mechanical Nociceptive Sensitivity in REV-ERBα Knock-out Mice
por: Lee, Jaehyun, et al.
Publicado: (2016)

Rev-erb-α regulates atrophy-related genes to control skeletal muscle mass
por: Mayeuf-Louchart, Alicia, et al.
Publicado: (2017)

REV-ERBα reduction is associated with clinicopathological features and prognosis in human gastric cancer
por: Wang, Xiaoshan, et al.
Publicado: (2018)

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation
por: Pariollaud, Marie, et al.
Publicado: (2018)

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
por: Zhuang, Xiaodong, et al.
Publicado: (2019)

Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα
por: Altman, Brian J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_v9qf43nmkof7uk7nlqmgjl5otq