Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities

BACKGROUND: Based on previous studies highlighting that the induction of cyclooxygenase-2 (COX-2) and high prostaglandin E2 (PGE2) levels contribute to the pathogenesis of malignant pleural mesothelioma (MPM), and that aromatase (CYP19A1), an enzyme that plays a key role in estrogen biosynthesis, al...

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Detalles Bibliográficos
Autores principales: Nuvoli, Barbara, Antoniani, Barbara, Libener, Roberta, Maconi, Antonio, Sacconi, Andrea, Carosi, Mariantonia, Galati, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369782/
https://www.ncbi.nlm.nih.gov/pubmed/34404424
http://dx.doi.org/10.1186/s13046-021-02050-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369782/
https://www.ncbi.nlm.nih.gov/pubmed/34404424
http://dx.doi.org/10.1186/s13046-021-02050-1

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