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Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies

BACKGROUND: Metabolic reprogramming is a central feature in many cancer subtypes and a hallmark of cancer. Many therapeutic strategies attempt to exploit this feature, often having unintended side effects on normal metabolic programs and limited efficacy due to integrative nature of metabolic substr...

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Detalles Bibliográficos
Autores principales: Liefwalker, Daniel F., Ryan, Meital, Wang, Zhichao, Pathak, Khyatiben V., Plaisier, Seema, Shah, Vidhi, Babra, Bobby, Dewson, Gabrielle S., Lai, Ian K., Mosley, Adriane R., Fueger, Patrick T., Casey, Stephanie C., Jiang, Lei, Pirrotte, Patrick, Swaminathan, Srividya, Sears, Rosalie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369789/
https://www.ncbi.nlm.nih.gov/pubmed/34399819
http://dx.doi.org/10.1186/s40170-021-00263-8