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Time-dependent effect of 1,6-hexanediol on biomolecular condensates and 3D chromatin organization

BACKGROUND: Biomolecular condensates have been implicated in multiple cellular processes. However, the global role played by condensates in 3D chromatin organization remains unclear. At present, 1,6-hexanediol (1,6-HD) is the only available tool to globally disrupt condensates, yet the conditions of...

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Detalles Bibliográficos
Autores principales: Liu, Xinyi, Jiang, Shaoshuai, Ma, Lin, Qu, Jiale, Zhao, Longying, Zhu, Xing, Ding, Junjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369800/
https://www.ncbi.nlm.nih.gov/pubmed/34404453
http://dx.doi.org/10.1186/s13059-021-02455-3