Optimization of expression, purification and secretion of functional recombinant human growth hormone in Escherichia coli using modified staphylococcal protein a signal peptide

BACKGROUND: Human Growth Hormone (hGH) is a glycoprotein released from the pituitary gland. Due to the wide range of effects in humans, any disruption in hGH secretion could have serious consequences. This highlights the clinical importance of hGH production in the treatment of different diseases as...

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Detalles Bibliográficos
Autores principales: Rigi, Garshasb, Rostami, Amin, Ghomi, Habib, Ahmadian, Gholamreza, Mirbagheri, Vasiqe Sadat, Jeiranikhameneh, Meisam, Vahed, Majid, Rahimi, Sahel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369807/
https://www.ncbi.nlm.nih.gov/pubmed/34399745
http://dx.doi.org/10.1186/s12896-021-00701-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369807/
https://www.ncbi.nlm.nih.gov/pubmed/34399745
http://dx.doi.org/10.1186/s12896-021-00701-x

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