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Optimization of expression, purification and secretion of functional recombinant human growth hormone in Escherichia coli using modified staphylococcal protein a signal peptide
BACKGROUND: Human Growth Hormone (hGH) is a glycoprotein released from the pituitary gland. Due to the wide range of effects in humans, any disruption in hGH secretion could have serious consequences. This highlights the clinical importance of hGH production in the treatment of different diseases as...
Autores principales: | Rigi, Garshasb, Rostami, Amin, Ghomi, Habib, Ahmadian, Gholamreza, Mirbagheri, Vasiqe Sadat, Jeiranikhameneh, Meisam, Vahed, Majid, Rahimi, Sahel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369807/ https://www.ncbi.nlm.nih.gov/pubmed/34399745 http://dx.doi.org/10.1186/s12896-021-00701-x |
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