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RNA kinase CLP1/Cbc regulates meiosis initiation in spermatogenesis

CLP1, TSEN complex, and VCP are evolutionarily conserved proteins whose mutations are associated with neurodegenerative diseases. In this study, we have found that they are also involved in germline differentiation. To optimize both quantity and quality in gametes production, germ cells expand thems...

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Detalles Bibliográficos
Autores principales: Wu, Jianbo, Li, Xin, Gao, Zhiyang, Pang, Lin, Liu, Xian, Huang, Xiahe, Wang, Yingchun, Wang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369837/
https://www.ncbi.nlm.nih.gov/pubmed/33864361
http://dx.doi.org/10.1093/hmg/ddab107