ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins

Zinc transporter 8 (ZnT8) is an important zinc transporter highly expressed in pancreatic islets. Deficiency of ZnT8 leads to a marked decrease in islet zinc, which is thought to prevent liver diseases associated with oxidative stress. Herein, we aimed to investigate whether loss of islet zinc affec...

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Detalles Bibliográficos
Autores principales: Su, Wen, Feng, Mingji, Liu, Yuan, Cao, Rong, Liu, Yiao, Tang, Junyao, Pan, Ke, Lan, Rongfeng, Mao, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369884/
https://www.ncbi.nlm.nih.gov/pubmed/34413780
http://dx.doi.org/10.3389/fphar.2021.721471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369884/
https://www.ncbi.nlm.nih.gov/pubmed/34413780
http://dx.doi.org/10.3389/fphar.2021.721471

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