Low-Coverage Whole Genome Sequencing of Cell-Free DNA From Immunosuppressed Cancer Patients Enables Tumor Fraction Determination and Reveals Relevant Copy Number Alterations

Cell-free DNA (cfDNA) analysis is a minimally invasive method that can be used to detect genomic abnormalities by directly testing a blood sample. This method is particularly useful for immunosuppressed patients, who are at high risk of complications from tissue biopsy. The cfDNA tumor fraction (TF)...

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Detalles Bibliográficos
Autores principales: Bouzidi, Amira, Labreche, Karim, Baron, Marine, Veyri, Marianne, Denis, Jérôme Alexandre, Touat, Mehdi, Sanson, Marc, Davi, Frédéric, Guillerm, Erell, Jouannet, Stéphanie, Charlotte, Frédéric, Bielle, Franck, Choquet, Sylvain, Boëlle, Pierre-Yves, Cadranel, Jacques, Leblond, Véronique, Autran, Brigitte, Lacorte, Jean-Marc, Spano, Jean-Philippe, Coulet, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369887/
https://www.ncbi.nlm.nih.gov/pubmed/34710202
http://dx.doi.org/10.3389/fcell.2021.661272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369887/
https://www.ncbi.nlm.nih.gov/pubmed/34710202
http://dx.doi.org/10.3389/fcell.2021.661272

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