Antitumor Effect of Fluoxetine on Chronic Stress-Promoted Lung Cancer Growth via Suppressing Kynurenine Pathway and Enhancing Cellular Immunity

Background: Chronic stress promotes cancer growth. Antidepressant fluoxetine (FLX) is usually prescribed for cancer patients with comorbid depression. FLX displays inhibition on cancer cell proliferation, however, the in vivo activity has not been investigated. Methods: We explored the antitumor eff...

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Detalles Bibliográficos
Autores principales: Yang, Zhen, Li, Zhuman, Guo, Zhijun, Ren, Yu, Zhou, Ting, Xiao, Zhijun, Duan, Jingjing, Han, Chuangchuang, Cheng, Yuanchi, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369900/
https://www.ncbi.nlm.nih.gov/pubmed/34413774
http://dx.doi.org/10.3389/fphar.2021.685898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369900/
https://www.ncbi.nlm.nih.gov/pubmed/34413774
http://dx.doi.org/10.3389/fphar.2021.685898

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