Heterozygosity of the Alpha 1‐Antitrypsin Pi*Z Allele and Risk of Liver Disease

The serpin family A member 1 (SERPINA1) Z allele is present in approximately one in 25 individuals of European ancestry. Z allele homozygosity (Pi*ZZ) is the most common cause of alpha 1‐antitrypsin deficiency and is a proven risk factor for cirrhosis. We examined whether heterozygous Z allele (Pi*Z...

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Detalles Bibliográficos
Autores principales: Hakim, Aaron, Moll, Matthew, Qiao, Dandi, Liu, Jiangyuan, Lasky‐Su, Jessica A., Silverman, Edwin K., Vilarinho, Silvia, Jiang, Z. Gordon, Hobbs, Brian D., Cho, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369947/
https://www.ncbi.nlm.nih.gov/pubmed/34430780
http://dx.doi.org/10.1002/hep4.1718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369947/
https://www.ncbi.nlm.nih.gov/pubmed/34430780
http://dx.doi.org/10.1002/hep4.1718

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