Investigation of the association between cerebral iron content and myelin content in normative aging using quantitative magnetic resonance neuroimaging

Myelin loss and iron accumulation are cardinal features of aging and various neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for myelin synthesis and maintenance. An emerging hypothesis in Alzheimer’s disease research suggests that myelin breakdown releases sub...

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Detalles Bibliográficos
Autores principales: Khattar, Nikkita, Triebswetter, Curtis, Kiely, Matthew, Ferrucci, Luigi, Resnick, Susan M., Spencer, Richard G., Bouhrara, Mustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370037/
https://www.ncbi.nlm.nih.gov/pubmed/34139358
http://dx.doi.org/10.1016/j.neuroimage.2021.118267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370037/
https://www.ncbi.nlm.nih.gov/pubmed/34139358
http://dx.doi.org/10.1016/j.neuroimage.2021.118267

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