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Investigation of the association between cerebral iron content and myelin content in normative aging using quantitative magnetic resonance neuroimaging
Myelin loss and iron accumulation are cardinal features of aging and various neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for myelin synthesis and maintenance. An emerging hypothesis in Alzheimer’s disease research suggests that myelin breakdown releases sub...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370037/ https://www.ncbi.nlm.nih.gov/pubmed/34139358 http://dx.doi.org/10.1016/j.neuroimage.2021.118267 |