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Perturbation of ACE2 Structural Ensembles by SARS-CoV-2 Spike Protein Binding
[Image: see text] The human ACE2 enzyme serves as a critical first recognition point of coronaviruses, including SARS-CoV-2. In particular, the extracellular domain of ACE2 interacts directly with the S1 tailspike protein of the SARS-CoV-2 virion through a broad protein–protein interface. Although t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370119/ https://www.ncbi.nlm.nih.gov/pubmed/34383488 http://dx.doi.org/10.1021/acs.jctc.1c00325 |