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Pharmacokinetics and Bioequivalence of Isavuconazole Administered as Isavuconazonium Sulfate Intravenous Solution via Nasogastric Tube or Orally in Healthy Subjects

For critically ill patients with invasive fungal infections, a nasogastric (NG) tube can be an alternative route for administration of isavuconazonium sulfate (ISAVUSULF). This was a randomized, open-label, 2-period, 2-sequence single-dose crossover study comparing single doses of 372 mg ISAVUSULF i...

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Detalles Bibliográficos
Autores principales: Desai, Amit, Helmick, Melanie, Heo, Nakyo, Moy, Selina, Stanhope, Stephen, Goldwater, Ronald, Martin, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370193/
https://www.ncbi.nlm.nih.gov/pubmed/34181478
http://dx.doi.org/10.1128/AAC.00442-21