Novel Nonnucleoside Inhibitors of Zika Virus Polymerase Identified through the Screening of an Open Library of Antikinetoplastid Compounds

Zika virus (ZIKV) is a mosquito-borne pathogen responsible for neurological disorders (Guillain-Barré syndrome) and congenital malformations (microcephaly). Its ability to cause explosive epidemics, such as that of 2015 to 2016, urges the identification of effective antiviral drugs. Viral polymerase...

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Detalles Bibliográficos
Autores principales: Sáez-Álvarez, Yanira, Jiménez de Oya, Nereida, del Águila, Carmen, Saiz, Juan-Carlos, Arias, Armando, Agudo, Rubén, Martín-Acebes, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370225/
https://www.ncbi.nlm.nih.gov/pubmed/34152807
http://dx.doi.org/10.1128/AAC.00894-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370225/
https://www.ncbi.nlm.nih.gov/pubmed/34152807
http://dx.doi.org/10.1128/AAC.00894-21

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