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CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease
α-Synuclein, a key pathological component of Parkinson's disease, has been implicated in the activation of the innate and adaptive immune system. This immune activation includes microgliosis, increased inflammatory cytokines, and the infiltration of T cells into the CNS. More recently, peripher...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370411/ https://www.ncbi.nlm.nih.gov/pubmed/33704423 http://dx.doi.org/10.1093/brain/awab103 |