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Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish
The ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular proteins. Adequate proteasomal degradation of crucial transcription regulators ensures the proper development of neutrophils. The ubiquitin E3 ligase of Growth factor indepen...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370619/ https://www.ncbi.nlm.nih.gov/pubmed/34351909 http://dx.doi.org/10.1371/journal.pgen.1009693 |