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Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis

Visceral leishmaniasis is a protozoan disease associated with high fatality rate in developing countries. Although the drug pipeline is constantly improving, available treatments are costly and live-threatening side effects are not uncommon. Moreover, an approved vaccine against human leishmaniasis...

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Detalles Bibliográficos
Autores principales: Helou, Doumet Georges, Mauras, Aurélie, Fasquelle, François, Lanza, Juliane Sousa, Loiseau, Philippe M., Betbeder, Didier, Cojean, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370633/
https://www.ncbi.nlm.nih.gov/pubmed/34403413
http://dx.doi.org/10.1371/journal.pntd.0009627