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Standardization of DNA amount for bisulfite conversion for analyzing the methylation status of LINE-1 in lung cancer
Highly methylated Long Interspersed Nucleotide Elements 1 (LINE-1) constitute approximately 20% of the human genome, thus serving as a surrogate marker of global genomic DNA methylation. To date, there is still lacking a consensus about the precise location in LINE-1 promoter and its methylation thr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370637/ https://www.ncbi.nlm.nih.gov/pubmed/34403448 http://dx.doi.org/10.1371/journal.pone.0256254 |