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Standardization of DNA amount for bisulfite conversion for analyzing the methylation status of LINE-1 in lung cancer

Highly methylated Long Interspersed Nucleotide Elements 1 (LINE-1) constitute approximately 20% of the human genome, thus serving as a surrogate marker of global genomic DNA methylation. To date, there is still lacking a consensus about the precise location in LINE-1 promoter and its methylation thr...

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Detalles Bibliográficos
Autores principales: Pham, Duong Anh Thuy, Le, Son Duc, Doan, Trang Mai, Luu, Phuong Thu, Nguyen, Uyen Quynh, Ho, Son Van, Vo, Lan Thi Thuong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370637/
https://www.ncbi.nlm.nih.gov/pubmed/34403448
http://dx.doi.org/10.1371/journal.pone.0256254