A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex

RNA exosomopathies, a growing family of diseases, are linked to missense mutations in genes encoding structural subunits of the evolutionarily conserved, 10-subunit exoribonuclease complex, the RNA exosome. This complex consists of a three-subunit cap, a six-subunit, barrel-shaped core, and a cataly...

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Detalles Bibliográficos
Autores principales: Sterrett, Maria C., Enyenihi, Liz, Leung, Sara W., Hess, Laurie, Strassler, Sarah E., Farchi, Daniela, Lee, Richard S., Withers, Elise S., Kremsky, Isaac, Baker, Richard E., Basrai, Munira A., van Hoof, Ambro, Fasken, Milo B., Corbett, Anita H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370739/
https://www.ncbi.nlm.nih.gov/pubmed/34162742
http://dx.doi.org/10.1261/rna.078618.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370739/
https://www.ncbi.nlm.nih.gov/pubmed/34162742
http://dx.doi.org/10.1261/rna.078618.120

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