Genes with 5′ terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein

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Viruses rely on the host translation machinery to synthesize their own proteins. Consequently, they have evolved varied mechanisms to co-opt host translation for their survival. SARS-CoV-2 relies on a nonstructural protein, Nsp1, for shutting down host translation. However, it is currently unknown h...

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Detalles Bibliográficos
Autores principales: Rao, Shilpa, Hoskins, Ian, Tonn, Tori, Garcia, P. Daniela, Ozadam, Hakan, Sarinay Cenik, Elif, Cenik, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370740/
https://www.ncbi.nlm.nih.gov/pubmed/34127534
http://dx.doi.org/10.1261/rna.078661.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370740/
https://www.ncbi.nlm.nih.gov/pubmed/34127534
http://dx.doi.org/10.1261/rna.078661.120

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