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Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing

TNRC6 is a scaffolding protein that bridges interactions between small RNAs, argonaute (AGO) protein, and effector proteins to control gene expression. There are three paralogs in mammalian cells, TNRC6A, TNRC6B, and TNRC6C. These paralogs have ∼40% amino acid sequence identity and the extent of the...

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Detalles Bibliográficos
Autores principales: Johnson, Samantha T., Chu, Yongjun, Liu, Jing, Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370741/
https://www.ncbi.nlm.nih.gov/pubmed/34108231
http://dx.doi.org/10.1261/rna.078709.121