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Argonaute binding within human nuclear RNA and its impact on alternative splicing

Mammalian RNA interference (RNAi) is often linked to the regulation of gene expression in the cytoplasm. Synthetic RNAs, however, can also act through the RNAi pathway to regulate transcription and splicing. While nuclear regulation by synthetic RNAs can be robust, a critical unanswered question is...

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Detalles Bibliográficos
Autores principales: Chu, Yongjun, Yokota, Shinnichi, Liu, Jing, Kilikevicius, Audrius, Johnson, Krystal C., Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370746/
https://www.ncbi.nlm.nih.gov/pubmed/34108230
http://dx.doi.org/10.1261/rna.078707.121