Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation

Many antibiotics that bind to the ribosome inhibit translation by blocking the movement of tRNAs and mRNA or interfering with ribosome dynamics, which impairs the formation of essential translocation intermediates. Here we show how translocation inhibitors viomycin (Vio), neomycin (Neo), paromomycin...

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Detalles Bibliográficos
Autores principales: Belardinelli, Riccardo, Sharma, Heena, Peske, Frank, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370747/
https://www.ncbi.nlm.nih.gov/pubmed/34117118
http://dx.doi.org/10.1261/rna.078758.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370747/
https://www.ncbi.nlm.nih.gov/pubmed/34117118
http://dx.doi.org/10.1261/rna.078758.121

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