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Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation
Many antibiotics that bind to the ribosome inhibit translation by blocking the movement of tRNAs and mRNA or interfering with ribosome dynamics, which impairs the formation of essential translocation intermediates. Here we show how translocation inhibitors viomycin (Vio), neomycin (Neo), paromomycin...
Autores principales: | Belardinelli, Riccardo, Sharma, Heena, Peske, Frank, Rodnina, Marina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370747/ https://www.ncbi.nlm.nih.gov/pubmed/34117118 http://dx.doi.org/10.1261/rna.078758.121 |
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