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Intron 4–5 hTERT DNA Hypermethylation in Merkel Cell Carcinoma: Frequency, Association with Other Clinico-pathological Features and Prognostic Relevance

Merkel cell carcinoma (MCC) is an aggressive skin tumor with neuroendocrine differentiation, mainly affecting elderly population or immunocompromised individuals. As methylation of the human telomerase reverse transcriptase (mhTERT) has been shown to be a prognostic factor in different tumors, we in...

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Detalles Bibliográficos
Autores principales: Ricci, Costantino, Morandi, Luca, Ambrosi, Francesca, Righi, Alberto, Gibertoni, Dino, Maletta, Francesca, Agostinelli, Claudio, Corradini, Angelo Gianluca, Uccella, Silvia, Asioli, Silvia, Sessa, Fausto, La Rosa, Stefano, Papotti, Mauro Giulio, Asioli, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370894/
https://www.ncbi.nlm.nih.gov/pubmed/33909215
http://dx.doi.org/10.1007/s12022-021-09669-y