Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro

Epicardial formation is necessary for normal myocardial morphogenesis. Here, we show that differentiating hiPSC-derived lateral plate mesoderm with BMP4, RA and VEGF (BVR) can generate a premature form of epicardial cells (termed pre-epicardial cells, PECs) expressing WT1, TBX18, SEMA3D, and SCX wit...

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Detalles Bibliográficos
Autores principales: Tan, Jun Jie, Guyette, Jacques P., Miki, Kenji, Xiao, Ling, Kaur, Gurbani, Wu, Tong, Zhu, Liye, Hansen, Katrina J., Ling, King-Hwa, Milan, David J., Ott, Harald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370973/
https://www.ncbi.nlm.nih.gov/pubmed/34404774
http://dx.doi.org/10.1038/s41467-021-24921-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370973/
https://www.ncbi.nlm.nih.gov/pubmed/34404774
http://dx.doi.org/10.1038/s41467-021-24921-z

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