ZNF768 links oncogenic RAS to cellular senescence

RAS proteins are GTPases that lie upstream of a signaling network impacting cell fate determination. How cells integrate RAS activity to balance proliferation and cellular senescence is still incompletely characterized. Here, we identify ZNF768 as a phosphoprotein destabilized upon RAS activation. W...

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Detalles Bibliográficos
Autores principales: Villot, Romain, Poirier, Audrey, Bakan, Inan, Boulay, Karine, Fernández, Erlinda, Devillers, Romain, Gama-Braga, Luciano, Tribouillard, Laura, Gagné, Andréanne, Duchesne, Éma, Caron, Danielle, Bérubé, Jean-Sébastien, Bérubé, Jean-Christophe, Coulombe, Yan, Orain, Michèle, Gélinas, Yves, Gobeil, Stéphane, Bossé, Yohan, Masson, Jean-Yves, Elowe, Sabine, Bilodeau, Steve, Manem, Venkata, Joubert, Philippe, Mallette, Frédérick A., Laplante, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370976/
https://www.ncbi.nlm.nih.gov/pubmed/34404770
http://dx.doi.org/10.1038/s41467-021-24932-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370976/
https://www.ncbi.nlm.nih.gov/pubmed/34404770
http://dx.doi.org/10.1038/s41467-021-24932-w

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