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Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

Proximity labeling (PL) with genetically-targeted promiscuous enzymes has emerged as a powerful tool for unbiased proteome discovery. By combining the spatiotemporal specificity of PL with methods for functional protein enrichment, we show that it is possible to map specific protein subclasses withi...

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Detalles Bibliográficos
Autores principales: Qin, Wei, Myers, Samuel A., Carey, Dominique K., Carr, Steven A., Ting, Alice Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370977/
https://www.ncbi.nlm.nih.gov/pubmed/34404792
http://dx.doi.org/10.1038/s41467-021-25259-2