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LncRNA KCNQ1OT1 activated by c-Myc promotes cell proliferation via interacting with FUS to stabilize MAP3K1 in acute promyelocytic leukemia

Uncontrolled proliferation is the hallmark of cancer cells. Previous studies mainly focused on the role of protein-coding genes in cancer cell proliferation. Emerging evidence showed that long non-coding RNAs (lncRNAs) also play critical roles in cancer cell proliferation and growth. LncRNA KCNQ1OT1...

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Detalles Bibliográficos
Autores principales: Tang, Doudou, Luo, Yujiao, Jiang, Yafeng, Hu, Piao, Peng, Hongling, Wu, Shangjie, Zhang, Guangsen, Wang, Yewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371007/
https://www.ncbi.nlm.nih.gov/pubmed/34404765
http://dx.doi.org/10.1038/s41419-021-04080-1