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The development of L-type Ca(2+) current mediated alternans does not depend on the restitution slope in canine ventricular myocardium

Cardiac alternans have crucial importance in the onset of ventricular fibrillation. The early explanation for alternans development was the voltage-driven mechanism, where the action potential (AP) restitution steepness was considered as crucial determining factor. Recent results suggest that restit...

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Detalles Bibliográficos
Autores principales: Tóth, Noémi, Szlovák, Jozefina, Kohajda, Zsófia, Bitay, Gergő, Veress, Roland, Horváth, Balázs, Papp, Julius Gy., Varró, András, Nagy, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371021/
https://www.ncbi.nlm.nih.gov/pubmed/34404848
http://dx.doi.org/10.1038/s41598-021-95299-7