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Frequency-preference response in covalent modification cycles under substrate sequestration conditions

Covalent modification cycles (CMCs) are basic units of signaling systems and their properties are well understood. However, their behavior has been mostly characterized in situations where the substrate is in excess over the modifying enzymes. Experimental data on protein abundance suggest that the...

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Detalles Bibliográficos
Autores principales: Szemere, Juliana Reves, Rotstein, Horacio G., Ventura, Alejandra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371027/
https://www.ncbi.nlm.nih.gov/pubmed/34404807
http://dx.doi.org/10.1038/s41540-021-00192-8