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Combined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia

The return of blood flow to ischemic heart after myocardial infarction causes ischemia–reperfusion injury. There is a clinical need for novel therapeutic targets to treat myocardial ischemia–reperfusion injury. Here we screened for targets for the treatment of ischemia–reperfusion injury using a com...

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Detalles Bibliográficos
Autores principales: Heliste, Juho, Jokilammi, Anne, Vaparanta, Katri, Paatero, Ilkka, Elenius, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371130/
https://www.ncbi.nlm.nih.gov/pubmed/34404849
http://dx.doi.org/10.1038/s41598-021-96033-z