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Single cell morphology distinguishes genotype and drug effect in Hereditary Spastic Paraplegia

A central need for neurodegenerative diseases is to find curative drugs for the many clinical subtypes, the causative gene for most cases being unknown. This requires the classification of disease cases at the genetic and cellular level, an understanding of disease aetiology in the subtypes and the...

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Detalles Bibliográficos
Autores principales: Wali, Gautam, Berkovsky, Shlomo, Whiten, Daniel R., Mackay-Sim, Alan, Sue, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371156/
https://www.ncbi.nlm.nih.gov/pubmed/34404843
http://dx.doi.org/10.1038/s41598-021-95995-4