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Single cell morphology distinguishes genotype and drug effect in Hereditary Spastic Paraplegia
A central need for neurodegenerative diseases is to find curative drugs for the many clinical subtypes, the causative gene for most cases being unknown. This requires the classification of disease cases at the genetic and cellular level, an understanding of disease aetiology in the subtypes and the...
Autores principales: | Wali, Gautam, Berkovsky, Shlomo, Whiten, Daniel R., Mackay-Sim, Alan, Sue, Carolyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371156/ https://www.ncbi.nlm.nih.gov/pubmed/34404843 http://dx.doi.org/10.1038/s41598-021-95995-4 |
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