Efficacy of a combination therapy targeting CDK4/6 and autophagy in a mouse xenograft model of t(8;21) acute myeloid leukemia

One of the most frequent cytogenetic abnormalities in acute myeloid leukemia (AML) is t(8;21). Although patients with t(8;21) AML have a more favorable prognosis than other cytogenetic subgroups, relapse is still common and novel therapeutic approaches are needed. A recent study showed that t(8;21)...

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Detalles Bibliográficos
Autores principales: Matsuo, Hidemasa, Nakatani, Kana, Harata, Yutarou, Higashitani, Moe, Ito, Yuri, Inagami, Aina, Noura, Mina, Nakahata, Tatsutoshi, Adachi, Souichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371187/
https://www.ncbi.nlm.nih.gov/pubmed/34430715
http://dx.doi.org/10.1016/j.bbrep.2021.101099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371187/
https://www.ncbi.nlm.nih.gov/pubmed/34430715
http://dx.doi.org/10.1016/j.bbrep.2021.101099

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