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Designed Artificial Protein Heterodimers With Coupled Functions Constructed Using Bio-Orthogonal Chemistry

The formation of protein complexes is central to biology, with oligomeric proteins more prevalent than monomers. The coupling of functionally and even structurally distinct protein units can lead to new functional properties not accessible by monomeric proteins alone. While such complexes are driven...

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Detalles Bibliográficos
Autores principales: Johnson, Rachel L., Blaber, Hayley G., Evans, Tomas, Worthy, Harley L., Pope, Jacob R., Jones, D. Dafydd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371201/
https://www.ncbi.nlm.nih.gov/pubmed/34422774
http://dx.doi.org/10.3389/fchem.2021.733550