Anticancer activity of RAPTA-EA1 in triple-negative BRCA1 proficient breast cancer cells: single and combined treatment with the PARP inhibitor olaparib

RAPTA-EA1 is a promising glutathione transferase (GSTP-1) inhibitor that has previously been shown to inhibit the growth of various breast cancer cells. We studied the anticancer activity of RAPTA-EA1 on triple-negative BRCA1 competent breast cancer MDA-MB-231 cells. MDA-MB-231 cells are significant...

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Detalles Bibliográficos
Autores principales: Hongthong, Khwanjira, Nhukeaw, Tidarat, Temboot, Pornvichai, Dyson, Paul J., Ratanaphan, Adisorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371217/
https://www.ncbi.nlm.nih.gov/pubmed/34430738
http://dx.doi.org/10.1016/j.heliyon.2021.e07749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371217/
https://www.ncbi.nlm.nih.gov/pubmed/34430738
http://dx.doi.org/10.1016/j.heliyon.2021.e07749

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