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Dual DNA Transfection Using 1,6-Hexanedithiol-Conjugated Maleimide-Functionalized PU-PEI(600) For Gene Correction in a Patient iPSC-Derived Fabry Cardiomyopathy Model

Non-viral gene delivery holds promises for treating inherited diseases. However, the limited cloning capacity of plasmids may hinder the co-delivery of distinct genes to the transfected cells. Previously, the conjugation of maleimide-functionalized polyurethane grafted with small molecular weight po...

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Detalles Bibliográficos
Autores principales: Chien, Chian-Shiu, Chien, Yueh, Lin, Yi-Ying, Tsai, Ping-Hsing, Chou, Shih-Jie, Yarmishyn, Aliaksandr A., Rastegari, Elham, Wang, Ting-Xian, Leu, Hsin-Bang, Yang, Yi-Ping, Wang, Mong-Lien, Jheng, Ying-Chun, Lai, Henkie Isahwan Ahmad Mulyadi, Ching, Lo-Jei, Huo, Teh-Ia, Cherng, Jong-Yuh, Wang, Chien-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371449/
https://www.ncbi.nlm.nih.gov/pubmed/34422789
http://dx.doi.org/10.3389/fcell.2021.634190