Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation

Phenazopyridine is a widely used drug against urinary tract pain. The compound has also been shown to enhance neural differentiation of pluripotent stem cells. However, its mechanism of action is not understood. Based on its chemical structure, we hypothesized that phenazopyridine could be a kinase...

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Detalles Bibliográficos
Autores principales: Preynat-Seauve, Olivier, Nguyen, Evelyne Bao-Vi, Westermaier, Yvonne, Héritier, Margaux, Tardy, Sébastien, Cambet, Yves, Feyeux, Maxime, Caillon, Aurélie, Scapozza, Leonardo, Krause, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371461/
https://www.ncbi.nlm.nih.gov/pubmed/34421588
http://dx.doi.org/10.3389/fphar.2021.664608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371461/
https://www.ncbi.nlm.nih.gov/pubmed/34421588
http://dx.doi.org/10.3389/fphar.2021.664608

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