Cargando…
Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation
Phenazopyridine is a widely used drug against urinary tract pain. The compound has also been shown to enhance neural differentiation of pluripotent stem cells. However, its mechanism of action is not understood. Based on its chemical structure, we hypothesized that phenazopyridine could be a kinase...
Autores principales: | Preynat-Seauve, Olivier, Nguyen, Evelyne Bao-Vi, Westermaier, Yvonne, Héritier, Margaux, Tardy, Sébastien, Cambet, Yves, Feyeux, Maxime, Caillon, Aurélie, Scapozza, Leonardo, Krause, Karl-Heinz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371461/ https://www.ncbi.nlm.nih.gov/pubmed/34421588 http://dx.doi.org/10.3389/fphar.2021.664608 |
Ejemplares similares
-
Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells
por: Suter, David M, et al.
Publicado: (2009) -
Decreased Levels of SARS-CoV-2 Fusion-Inhibitory Antibodies in the Serum of Aged COVID-19 Patients
por: Malézieux-Picard, Astrid, et al.
Publicado: (2022) -
A Cellular Assay for Spike/ACE2 Fusion: Quantification of Fusion-Inhibitory Antibodies after COVID-19 and Vaccination
por: Abdul, Fabien, et al.
Publicado: (2022) -
Acquired methemoglobinemia from phenazopyridine use
por: Murphy, Travis, et al.
Publicado: (2018) -
Phenazopyridine as an innovative stain for permanent staining of trematodes
por: Fakhar, Mahdi, et al.
Publicado: (2016)